期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

黑素小体转运机制的研究进展 被引量：3

原文传递
导出
摘要 人皮肤颜色的形成主要受色素沉着过程的影响。皮肤色素沉着的过程在微观上表现为黑素在黑素细胞内合成，随后转移到周围的角质形成细胞并在其中分布、代谢。其中黑素小体起到重要作用，它是黑素合成、储存以及转运的细胞内场所。黑素转运的机制一直是近年来的研究热点，本文就黑素转运过程的最新研究进展综述如下。
作者 王艺淳 林新瑜
机构地区 泸州医学院临床医学系 四川省人民医院皮肤病性病研究所
出处 《中华医学美学美容杂志》 2013年第2期156-158,共3页 Chinese Journal of Medical Aesthetics and Cosmetology
关键词 黑素小体 转运机制 皮肤色素沉着 角质形成细胞 皮肤颜色 黑素细胞 黑素合成 黑素转运
分类号 R285 [医药卫生—中药学]
  • 相关文献

参考文献22

  • 1Van Den Bossche K, Naeyaert JM, Lambert J, et al. Thequest for the mechanism of melanin transfer. Traffic, 2006,7(7).769-778.
  • 2Scott G, Leopardi S,Printup S, et al. Filopodia are conduitsfor melanosome transfer to keratinocytes. J Cell Sci, 2002,115(Pt7):1441-1451.
  • 3俞大卫.肤色形成与黑素细胞进化[J].中华医学美学美容杂志,2009,15(3):214-216. 被引量：1
  • 4Stenmark H. Rab GTPases as coordinators of vesicle traffic.Nat Rev Mol Cell Biol,2009,10(8) :513-525.
  • 5Hume AN. Ushakov DS, Tarafder AK, et al. Rab27a andMyoVa are the primary Mlph interactors regulating melano-some transport in melanocytes. J Cell Sci, 2007,120(Ptl7):3111-3122.
  • 6Tarafder AK, Wasmeier C, Figueiredo AC, et al. Rab27a tar-geting to melanosomes requires nucleotide exchange but noteffector binding. Traffic,2011,12(8) : 1056-1066.
  • 7Figueiredo AC, Tarafder AK, Wasmeier C, et al. Rab3GEP isthe non-redundant guanine nucleotide exchange factor forRab27a in melanocytes. J Biol Chem,2008, 283 (34) : 23209-23216.
  • 8Chiaverini C,Beuret L, Flori E, et al. Microphthalmia-associ-ated transcription factor regulates RAB27 A gene expressionand controls melanosome transport. J Biol Chem, 2008,283(18):12635-12642.
  • 9Beaumont KA. Hamilton NA, Moores MT, et al. The recy-cling endosome protein Rabl7 regulates melanocytic filopodiaformation and melanosome trafficking. Traffic, 2011,12(5):627-643.
  • 10Sakuraba K, Hayashi N . Kawashima M, et al. Down-regula-ted PAR-2 is associated in part with interrupted melanosometransfer in pigmented basal cell epithelioma. Pigment CellRes, 2004,17(4):371-378.

二级参考文献29

  • 1Wu X,Hammer JA 3rd.Making sense of melanosome dynamics in mouse melanoeytes.Pigment Cell Res,2000,13 (4):241-247.
  • 2Cario-Andre M,Bessou S,Gontier E,et al.The reconstructed epidermis with melanocytes:A new tool to study pigmentation and photoprotection.Cell Mol Biol,1999,45 (7):931-942.
  • 3Gibbs S,Murli S,De Boer G,et al.Melanosome capping of keratinocytes in pigmented reconstructed epidermis:effect of ultraviolet radiation and 3-isobutyl-1-methyl-xanthine on melanogenesis.Pigment Cell Res,2000,13(6):458-466.
  • 4Tsatmali M,Aneans J,Thody AJ.Melanocyte function and its control by melanocortin peptides.J Histochem Cytochem,2002,50(2):125-134.
  • 5Prota G,Lamoreux ML,Muller J,et al.Comparative analysis of melanins and melanosomes produced by various coat color mutants.Pigment Cell Res,1995,8(3):153-163.
  • 6Voisey J,van Daal A.Agouti:from mouse to man,from skin to fat.Pigment Cell Res,2002,15(1):10-8.
  • 7Xiao L,Matsubayashi K,Miwa N.Inhibitory effect of the watersoluble polymer-wrapped derivative of fullerene on UVA-induced melanogenesis via downregulation of tyrosinase expression in human melanocytes and skin tissues.Arch Dermatol Res,2007,299(5-6):245-257.
  • 8Scott MC,Suzuki I,Abdel Malek ZA.Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors and by ultraviolet radiation.Pigment Cell Res,2002,15(6):433-439.
  • 9Suzuki I,Im S,Tada A,et al.Participation of the melanocortin-1 receptor in the UV control of pigmentation.J Invest Dermatol Sympproc,1999,4(1):29-34.
  • 10Kanetsky PA,Swoyer J,Panossian S,et al.A polymorphism in the agouti signaling protein gene is asassoeiated with human pigmentation.Am J Hum Genet,2002,70(3):770-775.

同被引文献38

  • 1王曦,石钰,C.Viennet,李利,P.Humbert.黄芪甲苷对人皮肤成纤维细胞增殖和凋亡的影响[J].中华医学美学美容杂志,2006,12(2):93-97. 被引量：35
  • 2Lindhurst MJ,Wang JA,Bloomhardt HM,et al.AKT1 gene mutation levels are correlated with the type of dermatologic lesions in patients with Proteus syndrome[J].J Med Genet,2013,24(10):1038.
  • 3Thiffault I,Schwartz CE,Der Kaloustian V,et al.Mutation analysis of the tumor suppressor PTEN and the Glypican 3 (GPC3) gene in patients diagnosed with Proteus syndrome[J].Am J Med Genet,2004,130A(2):123-127.
  • 4Turner JT,Cohen MM Jr,Biesecker LG.A reassessment of the Proteus syndrome literature:application of diagnostic criteria on published cases[J].Am J Med Genet,2004,130A(2):111-122.
  • 5Cohen Jr MM,Hayden PW.A newly recognized hamartoma tous syndrome[J].Birth Defects Orig Artic Ser,1979,15(5B):291-296.
  • 6Biesecker LG,Peters KF,Darling TN,et al.Clinical differentiation between Proteus syndrome and hemihyperplasia:description of a distinct form of hemihyperplasia[J].Am J Med Genet,1998,79(4):311-318.
  • 7Cohen MM Jr.Proteus syndrome // Cohen MM Jr,Neri G,Weksberg R,editors.Overgrowth syndromes,Chapter 9[M].New York:Oxford University Press,2002:75-110.
  • 8Jamis Dow CA,Turner J,Biesecker LG,et al.Radiologic manifestations of Proteus syndrome[J].RadioGraphics,2004,24(4):1051-1068.
  • 9Biesecker L.The challenges of Proteus syndrome:diagnosis and management[J].Eur J Hum Gene,2006,14(11):1151-1157.
  • 10Cohen MM Jr.Putting a foot in one's mouth or putting a foot down:nonspecificity vs.specificity of the connective tissue nevus in Proteus syndrome[J].Proc Greenwood Genet Ctr,1995,14(1):11-13.

引证文献3

二级引证文献5

中华医学美学美容杂志
2013年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部