控制性超排卵与子宫内膜容受性

Controlled ovarian hyperstimulation and endometrial receptivity

控制性超排卵（COH）又称控制性卵巢刺激（COS），指以药物的手段在可控制的范围内诱发多卵泡的发育和成熟，其应用的对象本身多有正常的排卵功能，它是决定体外受精一胚胎移植（IVF—ET）成功与否的重要环节。子宫内膜容受性即子宫内膜接受胚胎的能力，子宫内膜间质腺体发生改变以允许胚胎定位、黏附、侵入接受的状态。

The use of controlled ovarian stimulation （COS）for assisted reproductive techniques （ARTs）aims to recruit a cohort of mature oocytes that can be fertilized to form a number of good-quality embryos to be transferred. The endometrial receptivity may be affected by the morphology, hormone receptors, paracrine,immune, gene expression, etc. The paper reviews the studies about impacts of COH on endometrial receptivity.