中西医结合治疗少腹血瘀证异位妊娠的临床观察

Clinical observation of treating ectopic pregnancy with syndrome of blood stasis in shaofu with Integrated Traditional Chinese Medicine and Western Medicine

目的为希望保留生育功能的异位妊娠患者提供一种更加有效的保守治疗方法。方法 120例异位妊娠患者随机分为2组,对照组:甲氨蝶呤肌内注射;治疗组:甲氨蝶呤肌内注射加自拟异位妊娠方口服。依据临床疗效加权综合评分法,统计分析2种治疗方法的近期疗效差异。结果 2组的2、3、4周的加权综合评分、总显效率、包块吸收,差异有统计学意义(P<0.01);2组的总有效率2、3周差异有统计学意义(P<0.01),4周差异无统计学意义(P>0.05);2组的血β-HCG仅在2周差异有统计学意义(P<0.01),3、4周差异无统计学意义(P>0.05);腹痛及阴道出血差异无统计学意义(P>0.05)。结论中西医结合治疗异位妊娠比甲氨蝶呤疗效更高,疗程更短,且安全、不良反应少,可作为临床保守治疗的首选方法。

Objective To provide a more effective expectant treatment method of ectopic preg- nancy to patients with fertility hope. Methods 120 cases of ectopic pregnancy were random- ly divided into control group treated with methotrexate and treatment group treated with Integrated Traditional Chinese Medicine and Western Medicine. Synthetic weighted mark method was applied to statistically analyze the short-term clinical effects of two treatment methods. Results Between 2 groups there were significant differences （/9〈0.01） in two weeks＇, 3 weeks＇ and 4 weeks＇ data of synthetic weighted mark, total apparent rate and mass absorbtion. Between 2 groups there were sig- nificant differences （P〈0.01） in 2 weeks＇ and 3 weeks＇ data of total effective rate, but no difference （P〉0.05） in the 4 weeks＇. There were significant differences（P〈0.01） in 2 weeks＇ and 3 weeks＇ data of serum human chorionic gonadotrophin β （β-HCG） but no difference （P〉0.05） in the 4 weeks＇. There were no difference （P〉0.05） in abdominal pain and colporrhagia between 2 groups. Conclusion Method of Integrated Traditional Chinese Medicine and Western Medicine can be used as the first clinical choice in expectant treatment of ectopic pregnancy as it has higher curative effect and shortet~ treatment course than method of methotrexate, and it is safe with less side effects.