化裁密蒙花散超声雾化联合雷火灸熏眼治疗干眼症的临床观察

Clinical effects of combined therapy of Buddleja officinali Powder of Ultrasonic Spray and Thunder-Fire Needle on Dry Eye syndrome

目的观察化裁密蒙花散超声雾化联合雷火灸熏眼治疗干眼症的临床疗效。方法将160例(160眼)干眼症患者随机分为(治疗A、B、C组,对照组)4组,每组40例。治疗A组采用化裁密蒙花散超声雾化治疗;治疗B组采用雷火灸熏眼治疗;治疗C组采用超声雾化联合雷火灸熏眼治疗;对照组采用人工泪液滴眼治疗。治疗4周后,统计疗效。分别记录治疗前后各组症状评分和泪液分泌实验、泪膜破裂时间,并进行统计分析。结果治疗A组(87.00%)、B组(84.00%)与对照组(82.00%)的有效率比较,差异无统计学意义(P>0.05);治疗C组总有效率为97.00%,和对照组比较差异有显著统计学意义(P<0.01)。治疗A组、B组、C组的显效率优于对照组;治疗A组、B组及对照组治疗后泪液分泌(SchirmerⅠ)试验和泪膜破裂时间(BUT)与治疗前比较差异有统计学意义(P<0.05);C组治疗后SchirmerⅠ试验和BUT与治疗前比较差异有统计学意义P<0.01,各组治疗后各检测指标优均于治疗前。结论化裁密蒙花散超声雾化联合雷火灸熏眼能明显改善干眼症患者的临床症状,改善SchirmerⅠ功能及泪膜破裂时间,疗效确切,且优于单用人工泪眼液;此两种方法联合治疗干眼症具有叠加效应。

Objective To observe the clinical effects of combined therapy of Buddleja officinali Powder of ultrasonic spray and Thunder-Fire Needle on dry eye. Methods 160 patients （160 eyes） of dry eye were randomly divided into 4 groups. The experimental group A （40 patients 40 eyes） was treated with Bnddleja officinali Powder of ultrasonic spray; the experimenta! group B（40 patients 40 eyes） was treated with Thunder-Fire Needle; the experimental group C （40 patients 40 eyes） was treated with two methods combining together; the control group （40 patients 40 eyes） was treated with artificial tears. Curative effects, clinical curative rates, Schirmer I test and Tear break-up time （BUT） were recorded before and after treatment and compared among 4 groups after 4 weeks treat- ment. Results The clinical curative rate differences among group A （87.00%）, group B （84.00%）and control group （82.00） had no statistical significance. The clinical curative rates of the experi- mental group C was 97.00%. The clinical curative rates of the experimental group A, B and C were better than control group, and the differences had statistical significance（P〈0.01）. The Schirmer I test and tearbreak-up time （BUT） after experiment were better than the data before experiment in all the experimental groups, and the differences had statistical significance. Conclusion Combined therapy of Buddleja officinali Powder of ultrasonic spray and Thunder-Fire Needle is effective in dry eye with high cure rate and great clinical application value; and combined therapy of two methods has stacking effect.