肝病患者医院感染的前瞻性研究

A prospective study of nosocomial infection in patients with liver diseases

目的 了解我院肝病患者的医院感染情况及其危险因素。方法 对 1996年 4月 1日～ 1998年 3月 31日新入院的 848例肝病患者的医院感染进行前瞻性调查。结果 医院感染率为 9.2 0 % ,其中重型肝炎的感染率最高 ,其次为肝硬化和重度慢性肝炎 ;医院感染部位分布 ,呼吸道占 44 .33 % ,腹腔 15 .46 % ,肠道 12 .37% ,胆系8.2 5 % ,口腔部位 7.2 2 % ,其他 12 .37%。结论 肝病患者病情危重、免疫功能低下、肝炎病毒重叠感染、严重并发症、侵袭性操作和广谱抗生素的使用是医院感染的易发因素 ;

OBJECTIVE To study the nosocomial infection in the patients with liver diseases and approach of risk factors.METHODS A prospective survey of nosocomial infection in 848 cases with various kinds of liver diseases was carried out in our hospital for a 24 month period.RESULTS Incidence of nosocomial infection in patients with liver diseases was 9.20%,osocomial infection rate in severe hepatitis was significantly higher than that in mild and moderate liver diseases.Infection of respiratory tract accounted for 44.33%,infection rate in abdominal cavity,intestinal tract, gallbladder and bile ducts,oral region,and other region were 15.46%,12.37%,8.25%,7.22% and 12.37%,respectively.CONCLUSIONS The factors related to nosocomial infection were the severity of liver diseases,cellular immunological condition,mixed infection of hepatitis virus,severe accompanying diseases,improper medical manipulations and use of broad spectrum antibiotics.Nosocomial infection affected the prognosis of liver diseases obviously.