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右美托咪啶在老年患者下肢骨科手术麻醉中的应用 被引量:8

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摘要 目的:观察右美托咪啶在老年患者下肢手术麻醉中的镇静效应。方法:选择60例71~85岁、ASAⅠ~Ⅲ级,拟行下肢骨科手术的老年患者,随机分为右美托咪啶组(D组)、丙泊酚组(P组),每组30例。记录麻醉前(T0)、椎管麻醉后(T1)及用药后5 min(T2)、15 min(T3)、30 min(T4)、60 min(T5)的MAP、HR、RR和Ramsay评分。结果:T3~T5时P组MAP显著低于T0时(P<0.05),也明显低于D组(P<0.05);T3~T5时两组HR低于T0时(P<0.05);T3~T5时两组RR均比T0时减慢,但P组明显(P<0.05);T2~T5时D、P组Ramsay评分高于T0时(P<0.05)。结论:右美托咪啶与丙泊酚均可用于老年患者下肢手术的镇静,但右美托咪啶0.5μg/kg泵注后继以0.5μg/(kg.h)输注镇静,患者呼吸循环系统更加稳定,效果更为理想。
出处 《中国民康医学》 2013年第7期48-49,共2页 Medical Journal of Chinese People’s Health
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