手性螺旋取代聚炔研究进展

Progress in Chirally Helical Substituted Polyacetylenes

天然大分子(如蛋白质、DNA等)能形成螺旋结构。受其启发,合成螺旋聚合物的设计制备一直是高分子学科领域重要的研究课题之一。基于我们课题组近年来所取得的研究成果,本文主要对光学活性螺旋取代聚炔的近期进展进行介绍,主要内容包括新型手性聚合物的制备及相关的应用研究,尤其是由光学活性螺旋聚炔构筑手性纳米粒子、手性核壳粒子、手性微球、手性(水)凝胶等;螺旋聚合物的应用研究则以手性识别、手性拆分、对映体诱导结晶、手性催化和手性控释为主。

Naturally occurring macromolecules like proteins and DNA form helical structures. Synthetic helical polymers as mimics of biomacromolecules have been attracting ever-growing attention. On the basis of our recent achievements in optically active helical substituted polyacetylenes, this review article briefly introduces novel chiral materials derived from helical polyacetylenes and their applications. Special attention is devoted to chiral nanoparticles, chiral core/shell particles, chiral mierospheres, and chiral （hydro）gels consisting of helical polyacetylenes. The applications of such helical polymeric materials in chiral recognition, chiral resolution, enantioselective crystallization, chiral catalysis, and cnantioselcctivecontrolled release are briefly summarized.