摘要
探究了木犀草素与锡(Ⅱ)配合物的最佳合成条件,制备木犀草素-锡(Ⅱ)配合物以作进一步的活性研究。以木犀草素与锡(Ⅱ)配位反应生成的配合物在乙醇溶液中吸光度大小为指标,在单因素实验的基础上,利用正交实验法探讨了配位反应溶液pH、原料物质的量比、反应液温度以及反应时间的影响,并探究配合物的UV-Vis特征。结果表明,最佳的合成条件为溶液pH4.5,木犀草素与氯化亚锡的物质的量比为1∶2.5,反应液温度为35℃,反应时间为5h。反应溶液pH对配合物的生成影响最显著,反应时间次之,原料物质的量比较小,温度影响最小。在最佳工艺条件下制备了木犀草素-锡(Ⅱ)配合物,产率为75.14%。
To investigate the optimal conditions of the chemical reaction between luteolin and Stannum（Ⅱ） for luteolin -Stannum （Ⅱ）complex, and to prepare the complex for the activity of further research.With the highest yield of the complex in ethanol solution through the determination of absorbance for index, on the basis of single factor experiment,orthogonal method was used to obtain the optimal conditions.The pH of the reaction solution, molar ratio of the raw materials, temperature and reaction time of the reaction in absolute ethyl alcohol solution were inspected,the UV-Vis spectroscopy of the complex was also studied.The results showed that the maximum yield of luteolin and Stannum （Ⅱ）complex was found at the conditions of pH4.5, molar ratio of 1：2,.5 （luteolin and stannous chloride） ,temperature 35℃ and 5 h of reaction time.The remarkable impact factor to the complex synthesis was the pH of reaction solution, secondly factor was reaction time,the molar ratio of raw material and temperature was the least.The yield was 75.14% at the optimal conditions.
出处
《食品工业科技》
CAS
CSCD
北大核心
2013年第9期246-249,共4页
Science and Technology of Food Industry
基金
国家科技支撑计划项目(2011BAI06B04)
河南省省院合作项目(102106000021)
河南省教育厅资助项目(12B350001)
