益气活血平肝汤治疗高血压肾病60例临床观察

Clinical Observation of Yiqi Huoxue Pinggan Decoction for Treating 60 Cases of Hypertension Nephropathy

目的:观察益气活血平肝汤结合常规西药治疗高血压肾病的临床疗效。方法:将120例高血压肾病患者随机分为对照组和治疗组各60例,对照组给予西药硝苯地平缓释片治疗;治疗组在对照组的基础上加用中药益气活血平肝汤治疗。观察2组临床疗效及24h尿蛋白定量、尿素氮(BUN)、肌酐(SC)r变化。结果:总有效率治疗组为87%,对照组为67%,2组比较,差异有显著性意义(P<0.05)。治疗后治疗组24h尿蛋白定量及BUN、SCr明显改善,与治疗前比较,差异均有显著性意义(P<0.05);2组治疗后各指标比较,差异也有显著性意义(P<0.05)。结论:在常规西药基础上结合中药益气活血平肝汤治疗高血压肾病疗效显著。

Objective： To observe the therapeutic effect of Yiqi Huoxue Pinggan Decoction plus conven- tional western medicine in treating hypertension nephropathy（HN）. Methods： One hundred and twenty HN patients were equally randomized into treatment group and control group. The two groups were given western medicine of Extended Release Nifedipine Tablets, and the treatment group was given oral use of Yiqi Huoxue Pinggan Decoction additionally. After treatment, the clinical effect was evaluated, and the changes of 24-hour urine protein content, blood urea nitrogen（BUN） and serum creatinine（SCr） were ob- served. Results： The total effective rate was 87% in the treatment group and 67% in the control group, the difference being significant（P〈0.05）. The content of 24-hour urine protein, BUN and SCr in both groups after treatment differed from those before treatment（P〈 0.05）, and the improvement in the treat- ment group was superior to that in the control group（P〈 0.05）. Conclusion： Yiqi Huoxue Pinggan Decoctionshows synergistic action on the effect of routine western medicine in treating HN.