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盐霉素针对肿瘤干细胞的治疗机制 被引量:1

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摘要 肿瘤干细胞是存在于肿瘤组织中的一小部分具有干细胞性质的细胞群体,它具有自我更新的能力,是形成不同分化程度肿瘤细胞和肿瘤不断扩大的源泉。而现有的治疗肿瘤的方法多是针对一般肿瘤细胞,而非肿瘤干细胞,治疗不彻底,仍会造成肿瘤的复发和转移。因此,开发新的药物杀灭肿瘤干细胞是现今治疗肿瘤的重点。盐霉素由于具有逆转多药耐药、抑制凋亡、调整细胞周期、抑制DNA修复等特点,可应用于肿瘤干细胞的治疗。
作者 孙冬妮
出处 《北方药学》 2013年第4期53-54,共2页 Journal of North Pharmacy
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