糖尿病伴轻度认知障碍患者生活质量与其认知功能的相关性

Correlations between Quality of Life and Cognitive Function among Diabetes Patients with Mild Cognitive Impairment

目的探讨糖尿病伴轻度认知障碍(mild cognitive impairment,MCI)患者生活质量与其认知功能的相关性。方法采用蒙特利尔认知评估量表、日常生活活动能力量表等对403例住院糖尿病患者进行MCI的筛查和诊断,对确诊为MCI的133例患者采用糖尿病患者特异的生活质量测定量表进行调查,并分析糖尿病伴MCI患者生活质量与其认知功能受损之间的关系。结果糖尿病伴MCI患者生活质量总体得分为[(62.99±10.319)分]明显高于认知功能正常组[(52.63±10.931)分],差异有统计学意义(P<0.01);不同年龄、体质指数、文化程度、病程及有无糖尿病并发症的糖尿病伴MCI患者间生活质量得分差异有统计学意义(P<0.05),其生活质量总分与认知功能总分、记忆、注意力、抽象能力、语言等维度得分呈负相关(P<0.05或P<0.01)。结论糖尿病伴MCI患者的认知水平明显影响该类患者的生活质量,临床上应重视并及早发现此类患者,在结合其他影响因素干预的前提下,积极控制认知功能损害的进一步发展,从而改善患者的生活质量。

Objective To analyze correlations between quality of life and cognitive function among diabetes patients with mild cognitive impairment. Methods Use the Montreal cognitive assessment （MoCA）, ac- tivity of daily living scale （ADL） and other scales to screen and diagnose mild cognitive impairment （MCI） from 403 inpatients with diabetes, and 133 patients with MCI were identified. Diabetes Patients Specific Quality of Life Determine Scale （DSQL） was used to investigate and analyze living quality and the correlations between cognitive damage and life quality. Results Overall level of QOL of diabetes patients with MCI （62.99±10. 319） is obviously higher than that of the normal group （52.63±10. 931） （P〈0.01）. Negative significant correlations was found between quality of life and MoCA score, memory, attention, abstract ability, language of cognitive domains（P〈0.05 or P〈0.01）. Conclusion The cognitive level of diabetes patients with MCI significantly affect the quality of life, we should pay more attention to find this kind of patients as early as possible in clinic, adopt corresponding measures to prevent the further development of cognitive damage control, so as to improve the life quality of patients.