2010～2011年广西临床内分泌激素检验室间质量评价结果分析

Analysis of external quality assessment result of clinical endocrine hormone from 2010 to 2011 in Guangxi

目的通过开展内分泌激素检验室间质量评价,提高广西临床内分泌激素检验质量,实现实验室间检验结果可比。方法分析2010～2011年内分泌激素检验室间质量评价结果,比较不同方法学、不同检测系统组结果的差异。结果 (1)各方法学组的CV值从小到大依次为电化学发光、微粒子酶免疫分析、时间分辨荧光、化学发光;(2)按检测系统分组,进口检测系统组内CV较满意,CV值在2.14%～23.95%;国产检测系统组内CV值不够满意,CV值在4.48%～51.85%;(3)各项目在不同检测系统间的靶值差异较大,内分泌激素项目的检验结果互认应在相同检测系统内进行;(4)2010～2011年连续4次平均及格率依次为74.04%、80.47%、85.26%和87.75%,年度合格率分别为55.85%和69.59%,该地区内分泌激素检验质量水平有了较大的提高,但项目年度合格率仍较低。结论该地区临床内分泌激素检验质量有了一定的提高,总体水平仍较低,需进一步规范与提高。

Objective To analyze the external quality assessment result of endocrine hormone and improve the quality of endocrine hormone tests in Guangxi, in order to achieve that testing results of the inter-laboratory are com- parable. Methods The external quality assessment result of endocrine hormone from 2010 to 2011 was analyzed. The results of different methods and different detection systems group were compared. Results （1）The coefficient of var- iation of different methods from small to large were electrochemiluminescence, microparticle enzyme immunoassay, time-resolved fluorescence immunoassay, and chemiluminescence, respectively. （2） CV in import detection system groups were acceptable, ranged from 2.14 % to 23.95 %, and CV in domestic detection system groups were dissatis- fied, ranged from 4.48 % to 51.85 %. （3）The targets in different detection systems were greatly varied, and the com- parability of the inter-laboratory results should be within the same detection system. （4） From 2010 to 2011, four consecutive average pass rates were 74.04%, 80.47%, 85.26% and 87.75%,respectively. The annual pass rates were 55.85% and 69.59% ,respectively. The endocrine hormone quality test level has been greatly improved. But the test item annual pass rate was still not good. Conclusion The endocrine hormone quality test has been improved, and need to further standardize and improve.