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表达Tie2单核巨噬细胞在肿瘤进展中的作用 被引量：2

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摘要 骨髓来源的髓系细胞在肿瘤的转移及血管生成的过程中发挥重要作用,其中一类表达Tie2的单核/巨噬细胞（Tie2＋monocyte/macrophage,TEM）是最近被发现,并引起关注的髓系细胞。在小鼠、人外周血和多个实体肿瘤组织等部位发现了TEMs的存在依据,并且通过与血管内皮细胞的相互作用,参与调节肿瘤微环境中血管的生成。
作者 吴丽 汪希鹏
机构地区 同济大学附属第一妇婴保健院妇科
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2013年第4期426-429,共4页 Chinese Journal of Immunology
基金 国家自然科学基金资助项目(No.81072136)
关键词 肿瘤组织 TIE2 单核巨噬细胞 单核 巨噬细胞 血管内皮细胞 血管生成 髓系细胞 肿瘤微环境
分类号 R73 [医药卫生—肿瘤]
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参考文献29

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同被引文献36

  • 1朱晓红,闫鸿,臧树良.内皮抑制因子抗肿瘤作用机制研究进展[J].中国公共卫生,2007,23(8):1011-1013. 被引量：2
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  • 6Matsubara T,Kanto T,Kuroda S,et al. TIE2-expressing monocytesas a diagnostic marker for hepatocellular carcinoma correlates withangiogenesis[ J]. Hepatology,2013,57(4) :1416 -1425.
  • 7Favre J, Terborg N, Horrevoets AJG. The diverse identity of an-giogenic monocytes [ J ]. European Journal of Clinical Investiga-tion,2013,43( 1) :100 - 107.
  • 8Murdoch C,Tazzyman S, Webster S,et al. Expression of Tie-2by human monocytes and their responses to angiopoietin-2[ J].The Journal of Immunology ,2007,178(11) :7405 - 7411.
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中国免疫学杂志
2013年 第4期

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