阻塞性睡眠呼吸暂停低通气综合征患者PSG诊断与生活质量相关性的研究

Study on the correlation between PSG diagnosis and the quality of life in patients with obstructive sleep apnea hypopnea syndrome

目的研究阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者多导睡眠监测(PSG)诊断与生活质量的相关性,为临床治疗OSAHS提供主观感受指标的参考。方法 45例经PSG诊断为轻、中、重度的OSAHS患者,使用美国医学结局研究组的36项问卷简表(SF-36)评价患者的生活质量,利用直线回归分析和多重逐步回归分析等统计学方法进行分析。结果重度OSAHS较轻度患者SF-36六个维度分值低。PSG参数呼吸暂停低通气指数(AHI)与SF-36中躯体疼痛(BP)呈正相关(P<0.05),PSG参数夜间最低血氧饱和度(LSaO2)和SF-36中生理功能(PF)、生理职能(RP)、总体健康(GH)呈正相关(P<0.05)。结论重度OSAHS较轻度患者生活质量受损严重;睡眠呼吸暂停和低通气及睡眠中低氧是影响OSAHS患者生活质量的相关因素。

Objective To study the correlation between PSG diagnosis and the quality of life in patients with obstructive sleep apnea hypopnea syndrome （OSAHS）. Methods 45 patients were diagnosed mild, moderate and severe OSAHS monitored by PSG. The life quality of patients was evaluated by MOS 36 - item short form health survey （ SF - 36）. The linear correlation and stepwise mul-tiple regression analysis were used to analyze the correlation among PSG parameter and SF-36 scores. Results The SF-36 scores of severe OSAHS patients was lower than that in mild ones. The AHI had positive correlation with body pain （P 〈 0. 05）. LSaO2 had posi-tive correlation with physical function, role physical, role physical and general health （P 〈 0. 05）. Conclusion The life quality of se-vere OSAHS patients is damaged. Sleep apnea - hypopnea syndrome and the lower oxygen saturation of night may be the reasons for re-ducing the life quality of the patients.