2Smith BR,Stabile BE. Extreme aggressiveness and lethali-ty of gastric adenocarcinoma in the very young[J]. ArchSurg,2009,144(2):506-510.
3Marina N.Gebhardt M,Teot L, et al. Biology and thera-peutie advances for pediatric osteosarcoma [ J]. Oncolo-gist,2004,9(4) :422~441.
4Bacci G,Longhi A,Fagioli F,et al. Adjuvant and neoadju-vant chemotherapy for osteosarcoma of the extremities:27year experience at Rizzoli Instute,Italy匸J], Eur J Career,2005,41(18).2836-2845.
8Bramer JA* ven-Linge JH,Grimer RJ,et al. Prognosticfactors in localized extremity osteosarcoma: a systematicreview[J], Eur J Surg Oncol,2009,35(10) : 1030-1036.
9Pakos EE,Nearchou AD,Grimer RJ,et al. Prognostic fac-tors and outcomes for osteosarcoma: an international col-laboration[J]. Eur J Cancer,2009,45(13) :2367-2375.
10Kim MS,Lee SY,Lee TR,et al. Prognostic nomogram forpredicting the 5-year probability of developing metastasisafter neo-adjuvant chemotherapy and definitive surgeryfor AJCC stage U extremity osteosarcoma [J]. Ann On-col,2009,20(5) :955-960.
3[1]Friedman MA,Carter SK.The therapy of osteogenic sarcoma:current status and thoughts for the future.J Surg Oncol,1972,4:482-510.
4[2]Bacci G,Ferrari S,Bertoni F,et al.Long-terra outcome for patients with nonmetastatic osteosarcoma of the extremity treated at the istituto ortopedico rizzoli according to the istituto ortopedico rizzoli/osteosarcoma-2 protocol:an updated report.J Clin Oncol,2000,18:4016-4027.
5[3]Bacci G,Longhi A,Fagioli F,et al.Adjuvant and neoadjuvant chemotherapy for osteosarcoma of the extremities:27 year experience at Rizzoli Institute,Eur J Cancer,2005,41:2836-2845.
6[4]Bacci G,Longhi A,Versari M,et al.Prognostic factors for osteosarcoma of the extremity treated with neoadjnvant chemotherapy:15-year experience in 789 patients treated at a single institution.Cancer,2006,106:1154-1161.
7[5]Shin Kyoo-Ho,Moon Seong-Hwan,Suh Jin-Suck,et al.Tumor volume change as a predictor of hemotherapeutic response in osteosarcoma.Clin Orthop Relat Res,2000,(376):200-208.
8[6]Eaneking WF,Spanier SS,Goodman MA.A system for the surgical staging of musculoskeletal sarcoma.Clin Orthop Relat Res,1980,(153):106-120.
9[7]Huvos AG,Rosen G,Marcove RC.Primary osteogenic sarcoma:pathologic aspects in 20 patients after treatment with chemotherapy en bloc resection,and prosthetic bone replacement.Arch Pathol Lab Med,1977,101:14-18.
10[8]Ferrari S,Bertoni F,Mercuri M,et al.Predictive factors of disease-free survival for non-metastatic osteosarcoma of the extremity:an analysis of 300 patients treated at the Rizzoli Institute.Ann Oncol,2001,12:1145-1150.
4Andreou D, Henrichs MP, Gosheger G, et al. New surgical treatment options for bone tumors[J]. Pathologe, 2014, 35 (Suppl2) : 232-236.
5StollKE, Miles HD, White JK, et al. Assessment of registration accuracy during computer-aided oncologic limb- salvage surgery[J]. Int J Comput Assist Radiol Surg, 2015,11 (13) :372-378.
6Harting MT, Lally KP, Andrassy RJ, et al. Age as a prognostic factor for patients with osteosareoma: An analysis of 438 patients[J]. J Cancer Res Clin Oncol, 2010, 136(4): 561-570.
7Bacei G, Longhi A, Versari M, et al. Prognostic factors for osteosarcoma of the extremity treated with neoadjuvant chemotherapy: 15-year experience in 789 patients treated at a single institution[J]. Cancer,2006,106(5):1154-1161.
8Ness KK, Neel MD, Kaste SC, et al. A comparison of function after limb salvage with non-invasive expandable or modular prostheses in children [J]. Eur J Cancer, 2014, 50 (18):3212-3220.
9ABED R, YOUNGE D. Surgical management of very large musculoskeletalsarcomas-recent advances in clinical onco- ogy[ J ]. Ann NYAcadSci, 2009,38 ( 11 ):77- 83.
10BACCI G,PICEI P,PIGNATFI G,et al. Neoadjuvant c- hemotherapy for don-metastatic esteosareoma of the ex- tremities[ J ]. CiinOrthopRdat Res, 1991,270(2) : 87-98.