中药佐治对弱视患儿视力和对比敏感度的影响

The effect of TCM on the vision and contrast sensitivity in treating infantile amblyopia

目的:探讨中药增视颗粒佐治儿童弱视的临床效果。方法:随机数字表法将159例弱视患儿分研究组和对照组,对照组采用遮盖、精细作业训练等治疗;研究组同时加服增视颗粒治疗6个月,测定视力和空间对比敏感度(Cntrast Snsitivity,CS),疗后随访视力2年。结果:①治疗6个月时,两组视力均有不同程度升高,研究组在停止治疗的2年内视力仍然呈升高趋势,而对照组有回降倾向,不同组间视力变化存在差异,F=14.213,P=0.000。不同时点的视力亦有统计学差异,F=59.364,P=0.000。②治疗后两组CS均有不同程度提高,6个月时研究组在4、8、12和16周期/度的空间对比敏感度高于对照组,P<0.05或P<0.01。结论:经典疗法联合中药增视颗粒治疗弱视患儿的效果优于单纯西医治疗。

Objective： To investigate the clinical effect of Zengshi granule on treating infantile amblyopia. Methods： 159 patients were randomly divided into two groups. The control group was treated with velation and meticulous training, while the treated group was given Zengshi granule more for 6 months. Results： The visions in both groups improved after 6 month treatment. The vision in the treated group continued to improve in the following 2 years, while that in the control group became to deteriorate, with significant differences （P〈0.05）. CS in both groups improved in different degree, and that in the treated group was higher than that in the control group （P〈0.05 or P〈0.01）. Conclusion： Traditional therapy combined with Zengshi granule had better effect than simple modem medicine on infantile amblyopia.