中成药不良反应的原因分析及预防措施

Cause analysis and protective measures of the adverse effects of Chinese formulated products

目的:探讨中成药不良反应的原因及预防措施,促进临床规范用药。方法:对我院2007年1月～2012年10月间报告的66例中成药不良反应病例资料进行回顾性分析。结果:66例中成药不良反应病例中,女性占53.03%,60岁以上老年人占54.54%,静脉用药发生率为92.42%,粉针剂型发生率为51.52%。结论:中成药不良反应的原因与特殊人群、中成药剂型及生产工艺不完善、临床应用不规范等因素有关;以中医理论为指导,辨证论治,重视患者个体差异,加强中成药制备工艺可一定程度上减少中成药不良反应发生。

Objective： To investigate the causes and protective measures of the adverse effects of Chinese formulated products. Methods： 66 patients collected from January 2007 to October 2012 were retrospectively analyzed. Results： Of all the 66 patients, 53.03% women and 54.54% seniors had adverse effects, while 92.42% the intravenous injection medicine and 51.52% injectable powder had adverse effects. Conclusion： The adverse effects of Chinese formulated products were connected with special patients, imperfect of TCM dosage form and producing technology and abnormal of clinical application.