一起家庭聚集性肾综合征出血热疫情调查处理

Investigation and control of a family outbreak of hemorrhagic fever with renal syndrome in Haidian district, Beijing

目的探讨家庭聚集性肾综合征出血热感染来源与传播途径,为制定科学、有效的防制措施提供理论依据。方法收集患者资料,包括病原学、流行病学、临床表现、病原学检查结果等。采用间接免疫荧光法进行血清学核实疫情。结果该起事件为一起由家鼠引起的经肠道感染的肾综合征出血热家庭聚集性疫情,共涉及病例2例,未发病感染者1例。结论多部门联防联控是出血热疫情处理的重要手段,防鼠灭鼠、高危人群疫苗应急接种和环境治理是预防和控制感染的重要措施。

Objective To explore infection sources and transmission routes of a family cluster of hemorrhagic fever with renal syndrome （ HFRS）, and to provide scientific evidence for disease prevention and control. Methods The data of patients including etiology, epidemiology, clinical symptoms and pathogen test results were collected. Serological diagnosis was conducted by indirect immunofluorescence （IFL） test to confirm the disease. Results This event was a family cluster of HFRS caused by Rattus norvegicus. The total 2 patients were infected the Hantavirus through intestinal transmission. There was one infected person without syndromes. Conclusion Cooperation of multiple departments was an important means for preventing HFRS. Rodent control, high risk people vaccination and environmental management were also essential measures for disease prevention and control.