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Ezrin高表达对肝细胞癌预后的影响

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摘要 Ezrin常与Moesin、Radixin共同表达于细胞膜内面,维持细胞形态和运动^[1]。我们曾经证实肝细胞癌(hepatocellular carcinoma,HCC)组织Ezrin表达和亚细胞定位发生改变^[2],
出处 《中华普通外科杂志》 CSCD 北大核心 2013年第4期307-308,共2页 Chinese Journal of General Surgery
基金 国家自然科学基金资助项目(30960120) 吉林省科技厅科技发展汁划基金资助项目(20090442)
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参考文献5

  • 1Zwaenepoel I, Naba A, Da Cunha MM, et al. Ezrin regulates microvillus morphogenesis by promoting distinct activities of Ep proteins. Mol Biol Cell, 2012, 23 : 1080- 1094.
  • 2林黎娟,金政,陈立天,王研,蔡英兰.组织芯片检测肝细胞癌中Ezrin蛋白的表达、定位及意义[J].中华普通外科杂志,2011,26(12):1049-1051. 被引量:2
  • 3Zheng S, Huang J, Zhou K, et al. 1713-Estradiol enhances breast cancer cell motility and invasion via extra-nuclear activation of actin-binding protein ezrin. PIxS One, 2011, 6 : e22439- 22448.
  • 4Jin J, Jin T, Quan M, et al. Ezrin overexpression predicts the poor prognosis of gastric adenocarcinoma. Diagn Pathol, 2012, 7:135- 142.
  • 5Meng Y, Lu Z, Yu S, et al. Ezrin promotes invasion and metastasis of pancreatic cancer cells. J Transl Med, 2010, 23: 61- 73.

二级参考文献5

  • 1Yeh CN,Pang ST,Chen TW,et al.Expression of ezrin is associated with invasion and dedifferentiation of hepatitis B related hepatocellular carcinoma.BMC Cancer,2009,9:233-242.
  • 2Sizemore S,Clicek M,Sizemore N,et al.Podocalyxin increases the aggressive phenotype of breast and prostate cancer cells in vitro through its interaction with Ezrin.Cancer Res,2007,67:6183-6191.
  • 3Sun CX,Robb VA,Gutmann DH.Protein 4.1 tumor suppressors:getting a FERM grip on growth regulation.J Cell Sci,2002,115:3991-4000.
  • 4Zeng HM,Xu LY,Xiao DW,et al.Altered expression of ezrin in esophageal squamos cell carcinoma.J Histochem Cytochem,2006,54:889-896.
  • 5高书颖,许丽艳,孟令英,崔磊,周飞,李恩民.ezrin基因在几种癌细胞中的表达及其5′侧翼区序列转录活性的鉴定[J].肿瘤防治研究,2008,35(1):1-4. 被引量:6

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