摘要
目的:用简单化学方法在处理过的牙釉质及不同基板表面原位合成形态可控的类釉质样氟磷灰石结构,模拟牙齿的自然组成及新貌,为新型抗龋材料的研究以及龋病治疗方法的革新提供理论及实验基础。方法:采用简单化学水热法筛选合成不同大小和形状、组成的氟磷灰石纳米棒的必要条件,并使纳米棒原位紧密排列在经处理的牙釉质及其他及其他基板表面,应用X射线衍射、扫描电镜评价新材料的理化性能。结果:获得结晶度高的氟磷灰石物质,并在基板表面有序紧密排列,晶体排列有一定的轴向取向,横截面直径为80nm,平均长度20μm,化学组成接近自然釉质。结论:新型材料能够初步模拟牙齿的形貌、组成及自然抗抗龋力,为将来直接或间接应用,将其加入到牙体材料或龋病预防和治疗中提供了前期研究基础。
Objective: To construct fluoridated hydroxyapatite(FA) enamel prism-like structures directly on the natural enamel surface and other plates with a simple chemical approach.Methods: Reaction conditions of hydrothermal technique were adjusted,including response time,temperature,dose,chelating agent types and so on,and FA enamel prism-like structures with different sizes and shapes were obtained.Scanning electron microscopy(SEM),powder X-ray diffraction(XRD),and physicochemical property were evaluated.Results: We have developed a film of compacted well-aligned FA crystals,which could grow on all kinds of plates.These nanorods were approximately 20μm in length and 800 nm in diameter whose physicochemical property were similar to natural enamels.Conclusions: The product could simulate the feature,component and decay resistance of human tooth enmel prism-like structure,which demonstrated the potential of applying nanotechnology to the direct creation of biomaterials with a specific biological architecture,providing the theory and experimental information for applications.
出处
《口腔医学研究》
CAS
CSCD
2013年第4期301-304,共4页
Journal of Oral Science Research
基金
类釉质样氟磷灰石的牙表面原位合成与性能研究(编号:201215050)
关键词
釉质龋
形态可控合成
氟磷灰石
Enamel caries Form controllable synthesis Fluorapatite