酮症酸中毒对I型糖尿病患儿认知功能影响的研究进展

Impact of type I diabetes mellitus complicated by ketoacidosis on cognitive function in children

糖尿病酮症酸中毒（diabetic ketoacidosis，DKA）是儿童糖尿病最常见的死亡原因之一，是儿科临床最常见的内分泌急症之一。随着对DKA研究的不断深入，DKA对中枢神经系统的影响已引起人们的重视。从宏观到微观对DKA引起认知功能障碍的机制的认识也在不断更新，本文就DKA引起认知功能障碍发病机制进展进行综述。

Diabetic ketoacidosis is one of the most common causes of death in the pediatric diabetes, and it is also one of the most common endocrine emergencies in children. With the further studies of this disease, more attentions are paid to the central nervous damage about DKA. The mechanisms about DKA-related cognitive dysfunction from the macro to the micro are constantly updated. This article gives a review on the pathogenesis of the cognitive dysfunction due to DKA.