化痰降浊法对痰湿壅盛型高血压病患者血浆同型半胱氨酸疗效观察

Clinical Efficacy of Dissipating Phlegm and Descending Turbid Method in Treating Plasma Homocysteine of Hypertensive Patients with Tanshiyongsheng Syndrome

目的:观察化痰降浊法对痰湿壅盛型高血压患者血浆Hcy的影响。方法:将76例患者随机分为治疗组和对照组,对照组36例采用口服依那普利、硝苯地平缓释片治疗。治疗组40例在对照组治疗基础上加用半夏白术天麻汤加减化痰降浊治疗,两组均以4周为1个疗程。观察两组治疗前后的血压、血浆Hcy并进行比较。结果:治疗组在降低血压及血浆Hcy的疗效上优于对照组,两组比较有显著性差异(P<0.05)。结论:化痰降浊法配合降压药治疗痰湿壅盛型高血压病能增强降压疗效,改善病人症状,并降低血浆Hcy浓度,从而更有效减少心脑血管事件的发生率。

Objective ： To observe the effects of dissipating phlegm and descending turbid method on the concentration of plasma Hey in hypertensive patients with Tanshiyongsheng syndrome. Methods ： 76 patients were randomly divided into treatment group and control group. 36 patients in control group were treated with enalapril, nifedipine sustained-release tablets. 40 patients in treatment group were treated with Banxia Baizhu Tianma Decoction for dissipating phlegm and descending turbid. 4 weeks was 1 course of treatment. Before and after treatment, blood pressure and plasma Hcy in two groups were observed and at the same time were compared between the two groups. Result ： The effect of treatment group was better than control group for lowering blood pressure and plasma Hcy. There were significant differences between two groups（ P〈0.05 ）. Conclusion： Dissipating phlegm and descending turbid decoction with antihypertensive drug treatment can enhance the antihypertensive efficacy, improve patient symptoms, reduce the concentration of plasma Hcy. And thereby it can effectively reduce the incidence of heart and brain blood vessel events.