思密达联合消旋卡多曲治疗小儿秋季腹泻的疗效观察

The Comparison of Therapeutic Effects on children Diarrhea Treated with smecta and Racecadotril Granules

目的探讨思密达联合消旋卡多曲治疗小儿秋季腹泻的治疗效果。方法将2011年10月至2012年3月我院112例住院治疗的秋季腹泻患儿随机分为对照组和观察组各56例,对照组在常规治疗基础上加用思密达,<1岁,1袋/日;1～2岁,1～2袋/日;>2岁,2袋/日,均分3次服用。观察组在对照组基础上加用消旋卡多曲1.5 mg/(kg.次),3次/日,总量不超过6 mg/(kg.d)。结果对照组和观察组总有效率为40%和52%,差异有统计学意义。结论思密达和消旋卡多曲联合治疗小儿秋季腹泻疗效较好,可以在临床上推广应用。

Objective To estimate the effect of administration of smecta and Racecadotril Granules For curing diarrhea in chil- dren. Methods From 2011 October to March 2012 112 eases in this hospital in - patient treatment of children autumn diarrhea were ran- domly divided into control group and observation group,each 56 cases,the control group was treated by Smecta, 〈 1 years old,1 bags per day ,1 - 2 1 - 2 bags per day ,more than 2 years old,2 bag/on average,3 doses, the observation group in the control group based on the use of raeecadotril （ 1.5 mg/kg,3 times/day,total amount not exceeding 6 mg/kg · d ）. Results The cured rate of controlled group was 40%, and of the observation group was 52% ,There was a statistic diffence （P 〈 0.05 ）. Conclusion-Comparison of therapeutic effects on children diarrhea treated with smecta and Racecadotril Granules is obvious, and is worth utilizing widely in clinic.