脊髓小脑性共济失调3型的研究进展

脊髓小脑性共济失调3型(SCA3)是遗传性脊髓小脑性共济失调最常见的亚型,发病方式可呈家族性,也可呈散发性,主要通过临床表现及基因检测确诊。目前无特效药物,临床治疗以延缓病情发展和对症治疗为主。随着人们生活水平的提高,该疾病越来越受到研究者的重视,现就近年来SCA3/MJD发病机制、临床特点、治疗进展进行系统的阐述。

Spinocerebellar ataxia type 3 is the most common subtype in Hereditary spinocerebellar ataxia, it begin with a familial,and can also be sporadic,it is Mainly diagnosed by clinical presentation and genetic testing. Now, there is no particular drug to control it,it is usually treated it by delaying its development and Symptomatic treatment, in order to Improving the self-care ability of the patients.With the development of people＂s live standard,it become increasingly concentrated by researchers. Now, I will summarize hepathogenesis, clinical features, treatment progress of the SCA3/MJD.