子宫内膜异位症相关性卵巢癌的临床病理特点

Clinicopathological Features of Endometriosis-associated Ovarian Cancer

[目的]探讨子宫内膜异位症相关性卵巢癌(EAOC)的临床病理特点。[方法]分析2002至2012年收治的27例EAOC和184例未合并子宫内膜异位症的卵巢癌患者临床资料,比较两组患者的年龄分布、病理类型、细胞分化和临床病理分期。[结果]EAOC患者平均年龄(47±15)岁,较未合并子宫内膜异位症的卵巢癌小5岁;病理类型以卵巢子宫内膜样癌和卵巢透明细胞癌为主,未合并子宫内膜异位症的卵巢癌以浆液性癌为主;手术病理分期早于未合并子宫内膜异位症的卵巢癌患者。[结论]与未合并子宫内膜异位症的卵巢癌相比,EAOC患者年龄更小,分期更早,病理类型以内膜样癌和透明细胞癌为主。

[ Purpose ] To investigate the clinicopathological features of endometriosis-associated ovarian cancer （EAOC）.[Methods] Twenty-seven cases with EAOC and 184 cases with ovarian cancer without endometriosis from 2002 to 2012 were analyzed retrospectively. Age distribu- tion, pathological types, differentiation and clinieopathological stages of the two groups were compared. [Resuhsl The average age was（47＋lS） years old in patients with EAOC, which was 5 years younger than that of ovarian cancer patients without endometriosis. Endometrioid type and clear-cell type were predominant in EAOC, however serous type was the common type in ovarian cancer patient without endometriosis. More earlier stages（surgieopathologic staging） were found in patients with EAOC than those in ovarian cancer patients without endometriosis. [Con- clusion] Compared with ovarian cancer without endometriosis, EAOC patients are younger, earlier stages, and pathologic types of endometrioid type and clear-cell type in the majority.