用新的紫外荧光光源对维生素D_2的最佳光合成

The Optimum Photochemical Synthesis of Vitamin-D_2 by New Ultraviolet Fluorescence Light Source

介绍了维生素 D2 (以下简称 VD2 )的光化反应与光照时间的关系 ,即由麦角甾醇为原料 ,在与之转化所需的最佳匹配光谱照射下 ,找到 VD2 的最佳光转化时间。结果表明 ,在 2 83 nm波长的紫外荧光光源照射下 ,其转化效果最佳。在此条件下麦角甾醇转化率随照射时间的增加而逐渐上升 ,但同时 VD2 的异构体 (副产物 )也随之增多 ,因此综合以上两种因素 ,从而可确定 1 8～ 2 1分钟是 VD2 光化反应的最佳时间段。

The relation between the transformation rates of photochemistry reaction and the time of illumination was described. Under the conditions of optimum matched spectrum, the ergosterol used as raw materials will beturned into vitamin D 2 and other byproducts. By series of experiments, it is found that the 283nm waved ultraviolet light source is fit for the photochemistry reaction.With this light source, the transform effect is best. With increasing illumination time, the transformation rate goes up and the content of the main product vitamin D 2 increases.But at the same time the content of the by products including tachysterol and lumisterol increase accordingly.So the time of illumination is a key factor in the production of vitamin D 2. We hope that these data on Vitamin D 2 will be usefal to producers, with which they can compare their manufacture parameters and improve their production technology.