诱发电位在小儿脑瘫诊断中的应用价值分析

An analysis on application value of evoked potential in diagnosis of cerebral palsy in infants

目的探讨诱发电位在小儿脑瘫诊断中的应用价值。方法以2009年1月～2012年12月期间收治的64例脑瘫患儿为研究对象,另外选取64例健康婴幼儿作为对照组,分别检测两组的脑干听觉诱发电位(BAEP),并观察和测量两组间Ⅰ、Ⅲ、Ⅴ波的潜伏期以及Ⅰ～Ⅲ、Ⅲ～Ⅴ、Ⅰ～Ⅴ波的峰间期的不同;将检测出的脑瘫患儿再分为BAEP正常组和异常组,分析两组患儿在头颅CT异常情况和脑瘫程度方面的差异。结果观察组的Ⅰ、Ⅲ、Ⅴ波的潜伏期和Ⅰ～Ⅲ、Ⅲ～Ⅴ、Ⅰ～Ⅴ波的峰间期均明显长于对照组,差异具有统计学意义;脑瘫患儿的BAEP正常组与异常组比较,异常组的头颅CT异常率以及中重度脑瘫所占比例均显著高于正常组,差异具有统计学意义。结论小儿脑瘫患者具有较高的BAEP异常率,BAEP对诊断脑瘫换的听觉损害、脑功能损害、病情严重程度均有一定的指导意义。

Objective To investigate the application value of evoked potential in diagnosis of cerebral palsy in infants. Methods Sixty-four cerebral palsy infants in our hospital from Jan 2009 to Dec 2012 were regarded as the objects of study. And, another 64 health infants were selected as control group. BAEP of infants in two groups were detected re- spectively. The differences in latent periods of Ⅰ,Ⅲ and V wave and interspike interval of Ⅰ-Ⅲ、Ⅲ-Ⅴ and Ⅰ-Ⅴ wave between two groups were observed and measured. The detected infants with cerebral palsy were divided into BAEP normal group and abnormal group. And, the differences in head CT and the degree of cerebral palsy between these two groups were observed. Results Latent periods of Ⅰ,Ⅲ and Ⅴ wave and interspike interval of Ⅰ-Ⅲ、Ⅲ-Ⅴ andⅠ-Ⅴ of observation group were obviously longer than those of control group. The differences had the statistical meaning. By comparing BAEP normal group with abnormal group, the abnormal index of head CT and middle and se- vere cerebral palsy of abnormal group were higher than those of normal group. The differences had the statistical meaning. Conclusion Cerebral palsy infants have higher BAEP abnormal rate. BAEP has certain directive significance for diagnosing hearing loss, cerebral injury and severity of the disease.