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对比剂急性肾损害的预防研究新进展 被引量:4

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摘要 随着放射显像技术尤其是冠状动脉介入的广泛开展,对比剂对肾功能的损害逐渐受到关注.对比剂性急性肾损害(contrast medium-induced acute kidney injury,CI-AKI)是指排除其他肾脏损害因素使用造影剂后3d内发生的急性肾功能损害.通常以48h内血肌酐比造影前基础水平上升25%,或是血肌酐上升44.2μmol/L为标准.最近出版的国外杂志,多以使用造影剂后3d内,血肌酐水平以〉44.2μmol/L为诊断标准.经历急诊介入治疗的CI-AKI发生率15%~30%,发生CI-AKI的患者院内病死率为未发生CI-AKI的急诊经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)患者的20倍.
出处 《河北医科大学学报》 CAS 2013年第4期486-490,共5页 Journal of Hebei Medical University
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