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氯诺昔康在预防全麻诱导期芬太尼诱发呛咳反应的研究

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摘要 目的:观察静注氯诺昔康对患者静注芬太尼诱发呛咳反应的预防作用。方法:择期全麻手术患者60例随机分为对照组(30例。静注0.9%NS2mL)和实验组(30例。静注氯诺昔康8mg)。15min后麻醉诱导:依次静注咪达唑仑0.1 mg/kg、芬太尼2.0μg/kg(时间<2 s)、丙泊酚1.5mg/kg、顺阿曲库铵0.2mg/kg。注药完毕后2min行气管插管。插管前观察呛咳发生情况。结果:与对照组比,实验组呛咳发生率和程度降低(P<0.05);余指标比无统计学意义。结论:静注氯诺昔康能有效预防患者全麻诱导期芬太尼诱发的呛咳反应。
出处 《汕头大学医学院学报》 2013年第1期40-41,共2页 Journal of Shantou University Medical College
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