摘要
目的 搜寻中国汉族人 X染色体的精神分裂症 (SP)易患性基因，分析 DXS1113多态性与 SP相关性及遗传学特征。方法运用扩增片段长度多态性 (Amp-FLP)检测技术，分析 30例 SP患者 DXS1113二核苷酸串联重复序列的多态性分布，并以 30例正常人作为对照。 结果 在对照组和 SP患者组中检出 12种 DXS1113多态性片段， SP组与对照组之间有 4种片段 (156bp、 168bp、 172bp、 174bp)的差异具有显著性
： Objective To search for a gene predisposing to schizophrenia(SP)on chromosome X in the Han nationality of Chinese,to explore the relationship between DXS1113 polymorphism with SP and feature of the genetics.Methods The dinucleotide repeat polymorphism distribution of DXS1113 of 30 patients with SP was examined with amplified fragment length polymorphism (Amp-FLP) examination technique.The control group consisted of 30 unrelated normal Chinese individuals.Results There was 12 alleles of DXS1113 among the patients and the normal controls.The results of statistical handing showed that four alleles (156bp,168bp,172bp,174bp)were significantly different(P
出处
《现代康复》
CSCD
2000年第9期1350-1351,共2页
Modern Rehabilitation
