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间充质干细胞与自身免疫性疾病 被引量:1

Mesenchymal stem cells and autoimmune diseases
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摘要 自身免疫性疾病的治疗一直以糖皮质激素和免疫抑制剂为主,但一些患者对糖皮质激素和免疫抑制剂反应不好或不能耐受,间充质干细胞可能成为一种新的辅助治疗手段。本文对间充质干细胞的特性及与自身免疫性疾病的关系进行综述。 The use of systemic steroid therapy is indispensable for the treatment of Autoimmune Diseases, and various immunosup- pressive agents are adjuvant therapies. But for some refractory autoimmune diseases, mesenchymal stem cells have become an effective therapy. The immunological characteristics of mesenchymal stem cells and the clinical progress in the treatment for autoimmune disease was reviewed in this paper.
作者 于小璇 付萍
出处 《皮肤病与性病》 2013年第2期85-86,89,共3页 Dermatology and Venereology
关键词 自身免疫性疾病 间充质干细胞 Autoimmune diseases Mesenchymal stem cells
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参考文献22

  • 1蒋志琼,唐中,袁国华,谭竟.间充质干细胞在T细胞免疫反应中的调节作用[J].基础医学与临床,2010,30(5):547-549. 被引量:3
  • 2Nie Y, Lau C, Lie A , et al. Defective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosus [ J]. Lupus, 2010, 19(7) : 850-859.
  • 3夏云飞,顾志峰.间充质于细胞与调节性T细胞的研究进展[J].Journal of Nantong University ( Medical Sciences) ,2010,30 ( 3 ) : 216-223.
  • 4Glennie S, Soeiro I, Dyson PJ, et al. Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells [ J ]. Blood, 2005, 105(7) : 2821-2827.
  • 5Zheng ZH, Li XY, Ding J, et al. Allogeneic mesenchymal stem cell and mesenchymal stem cell-differentiated chondrocyte suppress the re- sponses of type II collagen- reactive T ceils in rheumatoid arthritis [ J]. Rheumatology ( Oxford), 2008, 47( 1 ) : 22-30.
  • 6Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses [ J ]. Blood, 2005, 105 (4) : 1815 -1822.
  • 7Ramasamy R , Tong CK , Seow HF, et al. The imnmnosuppressive effects of human bone marrow-derived mesenchymal stem cells target T cell proliferation but not its effector function [ J ]. Cell Immunol, 2008, 251(2) : 131-136.
  • 8寿培舜,黄寅,苏娟娟,陈箐,李文钊,田新莉,许光武,任光文,时玉舫.间充质干细胞免疫抑制机制及在疾病中的应用[J].细胞生物学杂志,2009,31(1):15-20. 被引量:9
  • 9Corcione A, Benvenuto F, Ferretti E, el al. Human mesenchymal stem cell cells modulate B - cell functions [ J ]. Blood, 2006, 107 ( 1 ) : 367-372.
  • 10Ramasamy R, Fazekasova H, Lam EW, et al. Mesenchymal stem cells inhibit dendritic cell differentiation and function by preventing entry into the cell cycle [J]. Transplantation, 2007, 83( 1 ): 71-76.

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