心理干预联合中医药辨证治疗更年期功血临床观察

Effect of Psychological Intervention and Traditional Chinese Medicine in Treating Menopause Dysfunction Uterine Bleeding (DUB) Patients

目的:观察心理干预、认知疗法联合中医药辨证治疗更年期功血的临床疗效。方法:将112名确诊为更年期功血的患者,按随机数字表法分为对照组和治疗组,各56例。对照组予米非司酮,10 mg/d,治疗组在心理干预和认知疗法基础上,口服中药安坤汤(桃仁、当归、黄芪、赤芍、牡丹皮等,日1剂),连续给药3个月后,观察2组患者止血、贫血、子宫内膜厚度、中医证候积分和临床疗效的变化。结果:与对照组比较,治疗组止血时间明显缩短(P<0.05),子宫内膜厚度显著减小(P<0.05),贫血、中医症状疗效和临床疗效均有显著改善(P<0.05)。结论:心理干预、认知疗法与中药安坤汤合用可改善更年期功血患者生活质量,防止病情迁延、加重或复发,疗效较好。

Objective： To observe the clinical effects of psychological intervention, cognitive therapy and traditional Chi- nese medicine on menopause dysfunction uterine bleeding（DUB） patients. Method： 112 patients of DUB were divided into control group and experimental group randomly （according to the randomized digital table）. Patients of control group were given 10 mg mifepristone daily, patients of experimental group were treated with psychological intervention, cognitive therapy and traditional Chinese medicine （Ankun decoction ）, and the differences of hemostasis, anemia, thickness of Uterine En- dometrium, Traditional Chinese Medical （TCM） syndrome score and clinical effect between the control and experimental group were observed. Results： Compared with the control group, the patients＇bleeding time in the experimental group has sig- nificantly reduced （ P 〈 0.05）, thickness of Uterine Endometrium was reduced significantly, and anemia, TCM syndrome score and clinical effect were significantly improved at the same time. Conclusion：Psychological intervention and cognitive therapy combined with Ankun decoction can be used in the clinical treatment of menopause DUB patients, and its clinical ef- ficacy is superior to low dose mifepristone.