糖类抗原CA19-9诊断早期胰腺癌的效果观察

Detection of CA19-9 for the diagnosis of early pancreatic cancer

目的探讨肿瘤标志物糖类抗原CA19-9在诊断早期胰腺癌(PCA)中的作用。方法选取2009年3月至2010年10月间收治的35例胰腺癌患者为观察组,同时选择40位健康者为对照组。以化学发光免疫分析法对两组肿瘤标志物糖类抗原CA19-9水平进行检测并分析检测结果。结果观察组患者血清CA19-9阳性率为86.9%,对照组阳性率为7.3%,两组比较差异有统计学意义(P<0.05)。结论针对早期胰腺癌的检查,CA19-9检测有非常明显的临床价值,应该作为早期胰腺癌检查的可靠指标。

Objective To discuss the role of tumor markers carbohydrate antigen CA19-9 in the early diagnosis of pancreatic cancer （PCA）. Methods 35 pancreatic cancer patients were collected during March 2009 to October 2010 in our hospital, they were as the observation group, and the forty health peo- ples were selected as the control group. Using chemiluminescence immunoassay for the detection of tumor markers carbohydrate antigen CA19-9 level in the observation group and control group, and analyse the re- sults. Results Serum CA19-9 of patients in the observation group were significantly more than healthy per- son, the positive rate in observation group was 86. 9%, the positive rate in control group was 7. 3%, differ- ences between two groups had statistical significance （ P 〈 0. 05 ）. Conclusions For early pancreatic cancer in the inspection, CA19-9 detection has a very. significant clinical value, should be as early pancreat- ic cancer inspection reliability index.