超声乳化术对糖尿病性白内障角膜内皮细胞的影响

Influence of Cataract Phacoemulsification on Corneal Endothelial Cells in Diabetes

目的:探讨白内障超声乳化手术对糖尿病患者角膜内皮细胞的影响。方法:糖尿病组:糖尿病性白内障患者35例(40眼);对照组:单纯老年性白内障患者54例(60眼)。应用角膜内皮镜于术前及术后1周,1、3个月测量角膜内皮细胞密度、六角形细胞比率,分析结果。结果:糖尿病组和对照组内皮细胞密度、六角形细胞比率术前差异无统计学意义(P>0.05);两组术后角膜内皮细胞密度、六角形细胞比率均显著降低(P<0.05)。术后1周,1、3个月糖尿病组患者角膜内皮细胞丢失均明显高于对照组(P<0.01),糖尿病组患者六角形细胞比率均明显低于对照组(P<0.01)。结论:白内障超声乳化手术对角膜内皮细胞具有一定的损伤性,糖尿病患者对手术耐受性更低。

Objective： To investigate the influence of cataract phacoemulsifica tion on corneal endothelial cells in diabetes. Methods： 40 eyes of 35 cataract and diabetes patients in diabetic group and 60 eyes of 54 cataract patients withoutdiabetes in control group were involved in this study. The den sity and the percentage of hexagonal cells of the corneal endo thelium were measured before and on 1 week, 1 and 3 months after surgery. The results were analyzed. Results： In both group , the density and the percentage of hexagonal cells of the corneal endothelium decreased significantly after treatment （ P （ 0.05 ）. There is no statistical difference be- tween those of the two groups before treatment（P ~〉0.05）. the corneal endothelium loss in diabetes group was more significantly than those in control group and the percentage of hexagonal cells of the corneal endothelium in diabetes group was less significantly than those control group at 1 week; 1 and 3 months after treatment（P 〈（ 0.01）. Conclusion： The cataract phacoemulsification damages corneal endothelium more or less, and corneal en- dothelium of diabetics is more easy to be damaged.