基底动脉尖综合征28例临床分析

Clinical Analysis of 28 Cases with Top of The Basilar Artery Syndrome

目的:探讨基底动脉尖综合征(Top of the basilar artery syndrome,TOBS)的病因、高危因素及临床特点。方法:对28例TOBS的临床资料进行回顾性分析。结果:TOBS患者以中老年男性患者多见,其病因主要为栓塞、血栓形成,高危因素有高血压、糖尿病、高脂血症等,临床表现常以眩晕起病,伴有不同程度的意识障碍、眼球运动障碍和偏瘫等神经功能缺损。CT或MRI可以发现基底动脉顶端血管供血区的双侧两处以上梗死灶,以丘脑、中脑多见。结论:TOBS临床表现形式多样,其病死率、致残率较高,早期诊断和治疗对改善预后至关重要。

Objective： To study the top of basilar syndrome（TOBS） etiological factor high risk factor and clinical manifestation. Methods： To analysis the clinical data of 28 cases. Result： TOBS was common in middle- aged male patients. The etiological factor were embolism and thrombogenesis. High risk factor included hyperten- sion, diabetes, byperlipemia, and so on. The vertigo was common first sign in the clinical manifestationor with different degree of disturbance of consciousness eye movement disorder and hemiplegia and nerve function defect. CT and MRI showed more than two places or infarcts in the blood - supply of top of basal artery, the common focus was thalamus and midbrain. Conclusion： The basilar artery syndrome has all kinds of clinical manifestation. The high case fatality and mutilation were high. The early diagnosis and treatment to improving prognosis are important.