期刊文献+

美托洛尔对慢性心力衰竭患者心率震荡的影响 被引量:1

Therapeutic effects of metoprolol on heart rate turbulence in patients with congestive heart failure
原文传递
导出
摘要 【目的】研究美托洛尔干预慢性充血性心力衰竭后心率震荡的变化。【方法】选择有室性早搏的CHF患者60例,分为美托洛尔治疗组31例及对照组29例,所有患者行24 h动态心电图监测计算心率震荡的初始值(TO)、震荡斜率(TS)。【结果】美托洛尔治疗组TO>0,对照组则TO<0;美托洛尔治疗组的TS明显低于对照组。且治疗后HRT明显改善,TO下降,TS升高。【结论】美托洛尔可改善CHF的自主神经功能,进而改善HRT。 [ Objective ] To observe the therapeutic effect of metoprolol on heart rate turbulence (HRT) in patients with congestic heart failure (CHF). [Methods] There 60 patients with premature ventricular beats were divided into metoprolol group consisted of 31 cases and control group consisted of 29 cases . All patients were examined with ambulatory electrocardiogram monitoring for twenty-four hours, and turbulence onset (TO) and turbulence slope (TS) were analyzed, Patients in the metoprolol group were given orally metoprolol. [Results] TO were 〈0 in the control group and〉0 in the metoprolol group. TS was higher in the control group than that of the CHF group. TO decreased and TS increased respectively after oral administration of metoprolol for a month in the metoprolol group. [ Conclusion ] metoprolol can improve function of autonomic nerve in CHF patients in addition to improvement of HRT.
出处 《武警后勤学院学报(医学版)》 CAS 2013年第4期283-285,共3页 Journal of Logistics University of PAP(Medical Sciences)
关键词 慢性充血性心力衰竭 心率震荡 美托洛尔 Congestive heart failure Heart rate turbulence Metoprolol
  • 相关文献

参考文献6

  • 1Schmidt G, Molik M, Barthel P, et al. Heart rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarction[J]. Lancet, 1999, 353(7): 1390-1396.
  • 2Satw ani S, Dec GW. fladrenergic blockers in heart failure: review of mechanisms of action and clinical outcomes[J]. J Cumal of Card lovascular Pham Acology and Therapeclics, 2004,9:243-255.
  • 3Bauer A, Malik M, Barthel P, et al. Turbulence dynamics:an independent predictor of late mortality after acute myocardial infarction[J]. Int J Cardiol, 2006, 107:42-47.
  • 4Makikallio TH, Barthel P, Schneider R, et al. Prediction of sudden cardiac death after acute myocardial infarction:role of Holter monitoring in the modem treatment ear[J]. European Heart Journal, 2005, 26(8):762-769.
  • 5李志东,刘中国,王瑞英.心率震荡对心力衰竭患者死亡的预测价值及药物对心率震荡的影响[J].中国药物与临床,2007,7(10):746-748. 被引量:8
  • 6Wagstein F. Adrenergic beta -blocking agents in congestive heart failure due to idiopathic congestive heart failure[J]. Eur Heart J, 1995, 16(suppl):128.

二级参考文献9

  • 1Schmidt G, Malik M, Barthel P, et al. Heart-rate turbulence after ventrieular premature beats as a predictor of mortality after acute myocardial infarction. Lancet, 1999, 353:1390-1396.
  • 2Massie BM, Francis GS, Tandon PK, et al. Asymptomatic ventricular arrhythmias do not identify patients with severe heart failure at risk of sudden death.J Am Coll Cardiol, 1993,21:459.
  • 3Pedretti RF, Sarzi BS. Non-invasive sudden death risk stratification. Ital Heart J,2005,6:180-189.
  • 4Marine JE, Watanabe MA, Smith TW, et al. Effect of atropine on heart rate turbulence. Am J Cardiol,2002,89:767.
  • 5Lin LY, Lai LP, Lin JL, et al. Tight mechanism correlation between heart rate turbulence and baroreflex sensitivity:sequential autonomic blockade analysis. J Cardiovasc Electrophysiol,2002, 13:427.
  • 6Roach D, Koshman ML, Duff H, et al. Similarity of spontaneous and induced heart rate and blood pressure turbulence. Can J Cardiol, 2003,19( 12): 1375-1379.
  • 7Davies LC,Francis DP. Relation of heart rate and blood pressure turbulence following premature ventricular complexes to baroreflex sensitivity in chronic congestive heart failure. Am J Cardiol, 2001,87: 737-742.
  • 8Saxon LA. Improvement in heart rate turbulence as a measure of response to beta-blocker therapy for heart failure. J Cardiovasc Electrophysiol, 2004,15:757.
  • 9Lin LY, Hwang JJ, Lai LP, et al. Restoration of heart rate turbulence by titrated beta-blocker therapy in patients with advanced congestive heart failure:positive correlation with enhanced vagal modulation of heart rate. J Cardiovasc Electrophysiol, 2004, 15:752-758.

共引文献7

同被引文献7

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部