中医辨证治疗晚期NSCLC的临床回顾性分析

Retrospective Analysis of Traditional Chinese Medicine Syndrome Differentiation in Treatment of Advanced NSCLC

目的:分析晚期非小细胞肺癌3种中医症型之间生存期、疾病进展时间的差异,探索临床治疗晚期非小细胞肺癌的方案。方法:本研究方法纳入符合标准病历资料共104例,根据首诊病情分别纳入偏气虚组38例,偏痰湿组32例,偏阴虚组34例,对3组患者资料进行汇总分析。结果:经统计软件分析3组的中位生存期分别为580、737、711 d,1年累积生存率分别为42%、55%、52%,中位进展时间分别为300、632、377 d。结论:尽管受样本量少等因素限制,3组的中位生存时间、中位进展时间无显著性差异,但偏痰湿组较其他两组有治疗优势存在。

Objective：To analyze the differences among the three TCM syndrome types of advanced NSCLC in the survival time,time to progression,and to explore the clinical treatment of advanced non-small cell lung cancer programs.Methods：The research methods contained the standard medical record data of 104 cases.According to the first diagnosis of disease,they were divided into the deficiency of Qi group 38 cases,phlegm group 32 cases,deficiency of Yin group 34 cases,to summarize and analyze the data of three groups of patients.Results：Through the statistical analysis software,the median survival time of three groups were 580 d,737 d,711 d,and 1 year survival rates were 42%,55%,52%,the median time to progression was respectively 300 d,632 d,377 d.Conclusion：Despite the restricted small sample size and other factors,the three groups median survival time,median time to progression were not significant,but the phlegm group has therapeutic advantage.