血清铁蛋白与高血压脑出血后血肿周围脑水肿的关系研究

The study about association between serum ferritin and perihematoma edema in patients with hypertensive intracerebral hemorrhage

目的探讨血清铁蛋白与高血压脑出血后血肿周围脑水肿的关系。方法回顾性分析117例高血压脑出血患者,计算入院当天与入院后4d的血肿体积、脑水肿总体积、血肿周围脑水肿体积与血肿体积的比值,Spearman相关分析血肿周围脑水肿与血清铁蛋白等数据的关系。结果血肿周围脑水肿体积与血肿体积的比值在入院后4d时与血清铁蛋白成正相关(P=0.007),而入院当天与血清铁蛋白无明显相关性。结论血清铁蛋白是高血压脑出血后血肿周围脑水肿的一个重要指标。

Objective To explore the association between serum ferritin and perihematoma edema for the patients with hypertensive intracerebral hemorrhage Methods A retrospective analysis was conducted in 117 patients with hypertensive intracerebral hemorrhage and calculated the hematoma volume, edema volume, relative perihematoma edema volume on admission and the forth day, and then analyzed the relationship between serum ferritin level and relative perihematoma edema volume by Spearman correlation analysis. Results There was a significant positive correlation between serum ferritin and relative perihematoma edema volume on the forth day（P = 0.007）, but negative on admission. Conclusion Serum ferritin is an important indicator for perihematoma edema in patients with hypertensive intracerebral hemorrhage.