甲状腺功能亢进症与甲状旁腺功能的关系探讨

The functional change of Parathyroid in patients with hyperthyroidism

目的了解甲状腺功能亢进症(简称甲亢)患者甲状旁腺功能的变化,为临床治疗提供理论依据。方法对我院2011-06～2012-06收治63例甲亢患者进行实验室检查,按病程长短及甲亢严重程度分组,分别测定血清中甲状腺激素、甲状腺自身抗体、甲状旁腺激素(PTH)、血钙(Ca)、血磷(P)、血清维生素D3(VitD3)、碱性磷酸酶(ALP),判断甲状腺功能与甲状旁腺功能状态。结果重度甲亢组与中度、轻度甲亢组比较,PTH、VitD3、ALP均有显著性差异(P<0.05),而病程较长组与病程较短组比较,PTH、VitD3、ALP亦有显著性差异(P<0.05)。结论甲亢程度越重,病程越长,患继发性甲状旁腺功能亢进的风险越大。

Objective To explore the change of the function of parathyroid in patients with hyperthyroidism to provide theoretical evidence for clinical practice. Methods Serum thyroxin, thyroid autoantibody, parathormone, blood calci- um, serium inorganic phosphorus, VitD3, alkaline phosphatase was detected and Grouped by course length and se- verity of hyperthyroidism. Result Severe hyperthyroidism group and moderate, mild hyperthyroidism comparison, PTH, VitD3, ALP has significant differences P 〈 0.05, and comparison of course longer and shorter course groups, PTH, VitD3, ALP also showed a marked difference P 〈 0.05. Conclusions The hearier and longer the course of hy- perthyroidism, The greater the risk of secondary hyperparathyroidism.