浙江省嘉兴地区日本血吸虫病传播阻断16年后的临床分析

Clinical investigation on schistosomiasis after a 16-year-interruption program regarding its transmission, in Jiaxing region of Zhejiang province

目的分析浙江省嘉兴地区日本血吸虫病传播阻断16年后感染人群的结构变化和临床诊治情况。方法回顾性分析该地区近10年人院治疗的血吸虫病感染者临床资料，以及近8年有血吸虫虫卵沉积的病理标本。结果血吸虫病人院治疗总例数及并发症组、合并症组例数从2001年的194、78、116例分别增加到2010年的960、266、694例，三者例数逐年增加，且病例平均年龄也有增加，发病高峰年龄段均在60～74岁。有血吸虫虫卵沉积的病理标本数量从2003年的192例增加到2010年的298例，但占总病理标本的比例略有下降，平均年龄呈上升趋势。入院病例有虫卵沉积的部位依次为阑尾、结肠、直肠、胃、肝、胆囊、小肠。结论浙江省嘉兴地区血吸虫病传播阻断16年后感染者仍持续存在，但平均年龄却有增加。

Objective To investigate the epidemic pattern, diagnosis and treatment of schistosomiasis after the 16-years intervention program on its transmissionin Jiaxing region of Zhejiang province. Methods Clinical data of schistosomiasis patients during the last 10 years and pathological specimens with deposited schistosomal eggs during the last 8 years were retrospectively analyzed. Results The total numbers of schistosomiasis patients admitted to hospital increased from 194 in 2001 to 960 in 2010, and from 78 to 266 with complications. Number of the ones with accompanied diseases increased from 116 to 694. All the numbers of the above said three groups showed an yearly increase. The hardest hit age of the patients was between 60 and 74. The number of specimens with deposited schistosomal eggs increased from 192 in 2003 to 298 in 2010. While the ratio of specimens with deposited schistosomal eggs to the total number of pathological specimens became slightly decreasing, the average age of patients increased. Eggs were mainly deposited on appendix, colon, rectum, stomach, liver, gallbladder and small intestine. Conclusion Schistosomiasis still hit the Jiaxing region, with the average age of patients increased.