脊髓损伤与修复的关键科学问题——第81期“双清论坛”综述

KEY SCIENTIFIC ISSUES ON THE PATHOGENESIS AND REPAIR OF SPINAL CORD INJURY——Summary of 81th Shuangqing Forum

脊髓损伤的研究与治疗经过了漫长的探索,目前仍未发现针对脊髓损伤后微环境修复与神经再生的有效治疗方案。为了推动我国脊髓损伤基础和临床研究,国家自然科学基金委员会(以下简称自然科学基金委)近期召开了主题为"脊髓损伤与修复的关键科学问题"的第81期"双清论坛"。会议重点就脊髓损伤的临床研究进展、脊髓继发性损伤机制研究、脊髓损伤后修复和再生等关键科学问题的国内外研究前沿和研究热点展开讨论,同时结合我国的研究现状,分析我国在该领域的优势与不足,凝练并提出我国在脊髓损伤治疗领域中急需解决的重要基础科学问题,为我国未来5—10年的学科资助方向提出专家建议和参考。

Spinal cord injury （SCI） has remained a challenging area for scientists and clinicians due to the adverse and complex nature of its pathogenesis. To date, clinical therapies for debilitating SCI are largely ineffective. In order to promote the research and enhance the collaboration in this field, National Natural Science Foundation of China （NSFC） held the 81st Shuangqing Forum entitled ＂Critical scientific issues in spinal cord injury and its repair＂. This forum mainly focuses on the advance of clinical therapy, the patho- genesis of secondary injury, and the transplantation-based treatments after SCI. Moreover, key scientific issues on this field are compacted and discussed in the forum. Finally, suggestion are proposed for the basic and clinical research, and funding support for SCI in the coming decade in China.