麻醉前不同时机置胃管对手术患者皮质醇等相关因子的影响研究

Effect of cortisol and other related factors by time chosen for placing gastric tube before anesthesia on surgical patients

目的观察麻醉前不同时机置胃管对手术患者血液中皮质醇及血压、心率的影响。方法36例全麻手术需要置胃管的患者,随机分为两组:术晨病房常规置胃管组(对照组)和手术室全麻诱导前置胃管组(实验组),每组18例。分别监测术晨安静状态下(T0)、入手术室平静5min后(T1)、气管插管成功后5min(T2)、术毕麻醉停药前(T3)平均动脉压、心率、血清皮质醇的水平。结果两组多时段各观察指标比较,对照组平均动脉压、心率、血清皮质醇在T1、T2时段明显升高(P<0.05),T3时段有所回落,实验组相对较平稳,两组间比较(P<0.05)结论将手术患者置胃管时间放在手术室麻醉诱导前进行安全、可靠且应激反应小,值得推广。

Objective To study the effects of cortisol,blood pressure and heart rates by time chosen for setting stomach tube before anesthesia on surgical patients. Method Thirty-six surgical patients under general anesthesia who required stomach tube were randomly divided into two groups control group（setted stomach tube at ward）and experimental group （setted stomach tube before general anesthesia）. Mean arterial pressure, heart rates and serum cortisol were recorded at operation morning （T0）, before induction of anesthesia（T1 ）, 5 minutes after endotracheal intubation（T2 ） and the end of operation（T3 ）. Result There were significant difference beetween two groups in blood pressure, heart rates and serum cortisol level at varied time points. The experimental group was more smoothly than the control group. Conclusions Placement of a gastric tube before induction of general anesthesia was safe, reliable and lessens stress-induced reaction, and deserved spreading.