植物microRNA的生物信息学预测与分析

Prediction of MicroRNA in Plant Based on Bioinformatics

microRNA(miRNA)是一类广泛存在于真核生物中调控基因转录后表达的非编码小分子RNA。大量研究表明,miRNA在调节多种生物途径中起着重要的作用,采用生物信息学方法预测与分析miRNA是当前发现和鉴定植物miRNA的重要策略之一。本文总结了生物信息学预测植物miRNA及其靶基因的方法策略,阐述了生物信息学在植物miRNA研究中的重要作用,为今后的研究奠定了基础。

MicroRNA constitute a recently discovered class of non-coding small RNA, negatively regulate gene expression at the post-transcriptional level in eukaryotes. A large number of studies show that miRNA play important roles in regulating many biological approaches. Bioinformatics prediction and analysis of miRNA is one of the most important strategies for the discovery and identification in plant. The research content summarizes methods and strat- egies of bioinformatics prediction of miRNA and their target genes,expounds the important role of bioinformatics in the study of plant miRNA and is a foundation for future researches.