摘要
目的:观察灯盏花素对链脲佐菌素诱导糖尿病大鼠的膀胱逼尿肌的影响。方法:雌性SD大鼠分为正常对照组(C组)、糖尿病组(D组)、糖尿病灯盏花素治疗组(DD组)。以高糖高脂饮食及小剂量连脲佐菌素(30mg/kg)制备2型糖尿病大鼠模型。16周后光镜下观察膀胱逼尿肌在常规HE染色和苦味酸酸性品红(V-G)染色的改变。结果:糖尿病组大鼠与正常对照组差异明显,治疗组较糖尿病组明显下降。结论:在链脲佐菌素诱导糖尿病大鼠,灯盏花素具有保护膀胱逼尿肌功能。
Objective： To observe the effect of breviscapine on streptozotocin induced diabetic rats bladder detrusor. Methods： Female SD rats were divided into normal control group （group C）, diabetic group （group D）, diabetic breviscapine treatment group （group DD）. By high-fat diet and low dose with streptozotocin （30mg/kg） preparation of rat model of type 2 diabetes. 16 Zhou Houguang observation of bladder detrusor in routine HE staining and bitter acid fuchsin staining （V-G） changes. Results： Diabetic rats and normal control groups differed significantly, the treatment group was significantly decreased compared with the diabetic group. Conclusion： In the diabetic rats induced by STZ in, breviscapine could protect the detrusor function.
出处
《中国伤残医学》
2013年第4期56-57,共2页
Chinese Journal of Trauma and Disability Medicine
基金
深圳市2012深圳市科技局课题
立项编号201203317
