丙烯酰胺的环境暴露、生态行为与毒理效应研究进展

Environmental exposure, ecological behavior, and toxicological effect of acrylamide: A review

丙烯酰胺是具有神经毒性、生殖毒性和遗传毒性的潜在致癌物。它作为一种重要的化工原料,广泛应用于多种行业,使用量日益增加,其对环境和人类健康产生的危害逐渐引起关注。因此,研究其生态行为与毒理效应具有重要意义。本文概述了丙烯酰胺的环境暴露途径、在环境中的迁移行为、降解转化行为和生物转化及其代谢机制以及污染毒理效应,并依据目前存在的问题对今后的研究方向进行了展望,以期为今后环境中丙烯酰胺的毒性评估和污染防治提供参考。

Acrylamide is a potential carcinogen with neurotoxicity, reproductive toxicity, and genotoxicity. As an important chemical raw material, acrylamide is widely used in many indus- tries, and its application amount is increasing, being received increasing concerns due to its haz- ards to the environment and human health. Therefore, it is of great significance to study the eco- logical behavior and ecotoxicological effect of acrylamide. This paper summarized the environ- mental exposure routes of acrylamide, its translocation, degradation, and transformation behav- iors in the environment, its biotransformation and metabolic mechanisms, and its ecotoxicological effect. In light of the existed problems, the future research trends of acrylamide were also pros- pected, aimed to provide references to the toxicity assessment and the pollution prevention and treatment of acrylamide in the environment.