固尔苏治疗新生儿呼吸窘迫综合征影响因素分析

Factors Analysis on Neonatal Respiratory Distress Syndrome with Pulmonary Surfactant

目的:分析可能影响固尔苏治疗新生儿呼吸窘迫综合征的因素,为临床治疗评估提供参考。方法:回顾性收集应用固尔苏治疗新生儿呼吸窘迫综合征的130例患儿资料,记录性别、孕周、体重、Apgar评分、体位、剂量、使用固尔苏时间、血红蛋白、pH值等指标,应用多因素回归分析了解其可能的影响因素。结果:经多因素回归分析,孕周、体重、pH值、剂量等指标,经检验有统计学意义(P<0.05)。结论:孕周短、体重低、pH值低及剂量少可能是影响固尔苏治疗新生儿呼吸窘迫综合征的因素,临床应特别注意,以提高显效率,降低医疗风险。

Objective： Analyze factors which may affect Pulmonary surfactant in the treatment of neonatal respiratory distress syn- drome, provide a reference basis for clinical treatment evaluation. Methods ：130 cases who used Pulmonary surfactant to treat the neonatal respiratory distress syndrome in our pediatric hospital were collected; Record gender, gestational age, weight, and Apgar score, postures, dose, use Pulmonary surfactant time, hemoglobin, PH value,a total of nine indicators, the application of multiple factors regression analysis was applied to understand the possible influencing factors. Results：The multi-factor regression analysis, gestational weeks, weight, pH value, dose the inspection were statistically significant （P%0.05）. Conclusion ： Short that gestational weeks,low weight, pH value and low dose may be less influential Pulmonary surfactant in the treatment of neonatal respiratory distress syndrome factor, clinical special attention should be taken to these indicators, in order to improve efficiency and reduce the medical risk.