活肾汤辅助治疗老年稳定型心绞痛的临床研究

Research on the Clinical Effect of HuoShentang on Stable Angina Pectoris in Elderly Patients

目的:观察活肾汤辅助治疗老年稳定型心绞痛的临床疗效及其安全性。方法:90例老年稳定型心绞痛患者被随机分成两组,对照组予常规西药治疗,治疗组在对照组基础上加用中药活肾汤治疗,观察和比较两组治疗前后患者每周心绞痛发作的次数、疼痛程度、持续时间及硝酸甘油的消耗量,临床疗效,心电图疗效及不良反应的发生情况。结果:治疗组的临床总有效率和心电图总有效率分别为91.1%和82.2%,均明显高于对照组,分别为68.9%和66.7%(P<0.05)。治疗8周后,两组患者每周心绞痛发作次数和硝酸甘油消耗量均较治疗前显著减少(P<0.05),且治疗组患者每周心绞痛发作次数和硝酸甘油消耗量均较对照组显著减少(P<0.05)。两组不良反应的发生率比较无统计学差异(P>0.05)。结论:活肾汤辅助治疗老年稳定型心绞痛可显著提高常规治疗的临床疗效,且不增加不良反应的发生。

Objective： To observe the clinical therapeutic effect of HuoShentang in treating senile coronary stable angina pectoris and to explore its mechanism. Methods： Ninety old patients were randomly divided into two groups： patients in control group were treated with conventional medicine, while patients in treatment group were added HuoShentang on the basis of the routine methods in the con-trol group. Meanwhile, compared weekly the times of angina attacks, the pain level, duration, nitroglyccrin consumption and monitored electrocardiogram before and after the test between two groups. Results： The clinical curative effect of HuoShentang group was much better than control one （P〈0.05）, angina attacks were significantly reduced. Pain level was greatly relieved, and duration was obviously shortened, the nitroglycerin consumption was deceased （P〈0.05）. Conclusion： HuoShentang had better therapeutic effect on senile stable angina, the symptoms of patients were reduced, While the prognosis was enhanced by improving microcirculation of heart muscles, in-creased coronary blood flow. Thus greatly reduced the attacks of cardiovascular incidents.