影响慢性前列腺炎电针治疗效应的情志因素分析

Influence of Psychological Factor on Clinical Therapeutic Effects of Electric Acupuncture for Chronic Prostatitis

目的:分析影响慢性前列腺炎/慢性骨盆疼痛综合征(CP/CPPS)电针治疗效应的情志因素,为采取针对性的干预治疗提供科学依据。方法:收集的电针组77例CP/CPPS患者及对照组35例健康男性的临床资料,比较2组焦虑、抑郁症状检出率;电针组CP/CPPS患者接受4周的电针治疗,以治疗是否有效为终结事件,以治疗见效时间为时间变量,采用单因素及多因素的Cox回归模型分析情志因素对电针治疗效应影响。结果:电针组CP/CPPS患者焦虑及抑郁的检出率分别为25.974%和27.273%,明显高于对照组健康男性(P<0.05);电针治疗CP/CPPS有效率为87.012%,经Cox回归模型分析抑郁症状是影响CP/CPPS患者电针治疗效应的危险因素(P<0.05),而焦虑对治疗转归无影响(P>0.05)。结论:抑郁症状是影响CP/CPPS患者电针治疗效应的危险因素,应重视患者情志因素,必要时以采取更有针对性干预治疗。

Objective： To investigate the psychological factor influencing clinical therapeutic effects of Electric Acupuncture （EA） in treating Chronic Prostatitis/pelvic Chronic pain syndromes, and provide a scientific basis for psychotherapy. Methods：Clinical data of 77 CP/CPPS patients and 35 healthy male subjects were collected. The anxiety rate and depression symptom of the two groups were ana- lyzed. The CP/CPPS patients were treated with EA for 4 weeks. Based on the therapeutic results, the influence of psychological factors on the prognosis of CP/CPPS treated with EA was analyzed with univariate and multivariate Cox regression. Results ：The rates of anxiety and depression of the CP/CPPS in EA group were 25. 974% and 27. 273% , higher than those of normal controls （ P 〈0. 05 ）. The total effective rate of EA treating with CP/CPPS was 87. 012%. The analysis revealed that depression were the definite factor that negatively affected the prognosis of CP/CPPS treated by EA （ P 〈 0. 05 ）, while anxiety had no significant influence （ P 〉 0. 05 ）. Conclusion： De- pression is the definite factor that negatively affected the prognosis of CP/CPPS treated by EA. Importance should be attached to the psychological factors of CP/CPPS patients and proper psychological intervention is sometimes necessary.