中医药治疗银屑病湿热证用药规律分析

Analysis of Medication Rules of Corrective Treatment for Psoriasis with Damp-heat Syndrome

目的:总结中医治疗银屑病湿热证用药经验,分析银屑病湿热证用药规律,将中医理论与中药药理相结合,以指导临床治疗,提高疗效。方法:以"银屑病"为关键词,以"湿热证"为主题词,在1979-2011年中国期刊全文数据库(CNKI)和1998年-2012年万方医学期刊全文数据库资料内检索,重复文献除外。根据纳入和排除标准,搜集了用于治疗银屑病湿热证的中草药和基本方。结果:治疗银屑病湿热证的中草药共87味,基本方17首。土茯苓、白鲜皮、黄芩等23味中药治疗银屑病湿热证使用频率较高,属治疗银屑病湿热证的主药。药物归经主要归肝经,在治疗银屑病湿热证应重点从肝经论治。结论:治疗银屑病湿热证的主要方剂为:龙胆泻肝汤、萆薢渗湿汤、黄连解毒汤。

Objective： To summarize the experience of Chinese medicine treatment of psoriasis damp-heat syndrome, analyze the medica- tion rules of psoriasis damp-heat syndrome and integrate the theory of traditional Chinese medicine with pharmacology and medicinal chemistry to guide clinical treatment and improve efficacy. Methods： we used Psoriasis and damp-heat syndrome as keywords to search medical journals during 1979 - 2011 in China Academic Journal database （CNKI） and 1998 - 2012 Articles database. According to inclusion and exclusion criteria, we collected herbs and basic formulas for the treatment of psoriasis damp-heat syndrome. Results： We summarized 87 herbs and 17 basic formulas of psoriasis damp-heat syndrome. Twenty-three herbs in the treatment of psoriasis damp- heat syndrome had higher frequency of use, which mostly belong to liver channels. Conclusion ： Primary formulas for psoriasis damp-heat syndrome include Longdan XieGan Decoction, Bixie shenshi Decoction, Huanglianjiedu Decoction.