军事训练中运动性猝死高危人群筛查方法的研究

The screening method to high risk population of exercise-related sudden death when military training

目的探索军事训练中运动性猝死高危人群的筛查方法。方法通过问卷调查、物理查体、12导联心电图分析筛查，在960名士兵中筛选出高危人群作为高危组（120例），从剩余士兵中随机匹配正常对照组（120例）。比较两组士兵5000米跑步前、后（跑步前30rain，跑步后30min）血浆中肾上腺素（EPI）、一氧化氮（NO）、高敏c反应蛋白（CRP）浓度的变化（ELISA法检测）。结果两组士兵运动后血浆EPI、CRP水平较运动前显著增高，血浆NO水平较运动前显著降低（P〈0．05）。运动后高危组血浆EPI和CRP较对照组明显升高[（111．1±10.3）ng／L比（101．9±12．5）ng／L，（33．9±5．8）ng／L比（28．1±4．1）ng／L]，高危组NO较对照组显著降低[（102．3±12．3）}xmol／L比（108．3±9．7）mol／L]（P〈0．05）。结论本方法有助于对运动性猝死高危人群的筛选，对预防运动性猝死的发生有一定的指导意义。

Objective To investigate a method for screening high risk population of exerciserelated sud den death when military training. Methods In 960 soldiers, by using a questionnaire survey, physical examination and electrocardiogram, 120 soldiers were selected as highrisk populations, and random matching from the remain der of selection as a low risk group. The plasma Creactive protein, nitric oxide and epinephrine concentration changes were compared between high risk group and low risk group before and after exercise. Results After train ing the concentration of epinephrine and Creactive protein were significantly elevated than that before training, and concentration of nitric oxide decreased significantly in two groups （P〈0.05）. After training the concentration of epinephrine and Creactive protein were significantly elevated in high risk group than that in control group, and at the same time concentration of nitric oxide decreased significantly （P〈0.05）. Conclusion This method is highly viable to screen the high risk population of exerciserelated sudden death and have certain guiding significance to the prevention of exerciseinduced sudden death when military training.